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States Undercount Positive Rapid Tests, Masking the Spread of Disease

As rapid coronavirus tests are becoming more widely available, delivering results in minutes for patients in doctor's offices, nursing homes, schools and even the White House, officials warn of a significant undercount, blurring the virus's spread nationally and in communities where such tests are more commonly used.

Public health officials say that antigen tests, which are faster than polymerase chain reaction (P.C.R.) tests but less able to detect low levels of the virus, are an important tool for limiting the spread of the coronavirus. But they caution that with inconsistent public reporting, the case undercount may worsen as more “point-of-care” antigen tests, as well as D.I.Y. and home test kits, come on the market.

“We want to be sure that we’re not now saying, ‘there’s no disease,’ when there is lots of disease. All that’s happened is that the science with which we identify it has evolved,” said Janet Hamilton, the executive director of the Council of State and Territorial Epidemiologists, the group that helps the Centers for Disease Control and Prevention define cases of the coronavirus....

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Contract Tracing Problems: People Increasingly, ‘Have No Idea’ how they contracted COVID-19.

... As the coronavirus soars across the country, smashing daily records and surpassing nine million cases nationwide, tracing the path of the pandemic in the United States is no longer simply challenging. It has become nearly impossible.

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Remsdesvir: Some experts troubled about FDA approval for COVID-19 treatment

The United States reached a milestone, of sorts, when last week the Food and Drug Administration approved the first treatment for Covid-19.

The drug is called Veklury, although most people know it by its scientific name, remdesivir.

On Wednesday, its manufacturer, Gilead Sciences, said that remdesivir, which has been authorized for emergency use since the spring, had brought in $873 million in revenues so far this year and that it was the company’s second-best-selling drug in the third quarter, behind its H.I.V. drug, Biktarvy.

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New research shows that Covid-19 antibodies can neutralize the virus and last up to five months

There’s encouraging news about antibodies in a new paper published in the journal Science from researchers at New York City’s Mount Sinai Hospital. In their study of the antibody responses of patients with either mild or moderate Covid-19, antibody levels appeared to stay relatively stable for at least five months, and their presence was correlated with the inactivation of the virus.

Antibodies are molecules pumped out by the immune system in response to infection, and they have a role in preventing future infections, though exactly how they function within the context of Covid-19 isn’t clear yet. Scientists are urgently trying to figure out whether the presence of antibodies actually means a person is protected from future infection as well as how long antibodies last in the body. Knowing this is crucial, especially for vaccine development.

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Internal Documents Reveal COVID-19 Hospitalization Data The Government Keeps Hidden

As coronavirus cases rise swiftly around the country, surpassing both the spring and summer surges, health officials brace for a coming wave of hospitalizations and deaths. Knowing which hospitals in which communities are reaching capacity could be key to an effective response to the growing crisis. That information is gathered by the federal government — but not shared openly with the public.

NPR has obtained documents that give a snapshot of data the U.S. Department of Health and Human Services collects and analyzes daily. The documents — reports sent to agency staffers — highlight trends in hospitalizations and pinpoint cities nearing full hospital capacity and facilities under stress. They paint a granular picture of the strain on hospitals across the country that could help local citizens decide when to take extra precautions against COVID-19.

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